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NESC1088 UMIBIO. (Abstract last modified 23-MAY-2001)

UMIBIO, U Mill Bioassay Dosimetry Model

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Abstract Table of Contents:

NAME | COMPUTER | PROBLEM | SOLUTION | RESTRICTIONS | CPU | FEATURES | AUXILIARIES | STATUS | REFERENCES | REQUIREMENTS | LANGUAGE | OPERATING SYSTEM | OTHER RESTRICTIONS | AUTHOR | MATERIAL | CATEGORIES |

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1. NAME OR DESIGNATION OF PROGRAM - UMIBIO. 


2. COMPUTER FOR WHICH PROGRAM IS DESIGNED AND OTHER MACHINE VERSION PACKAGES AVAILABLE -

To request or retrieve programs click on the one of the active versions below. A password and special authorization is required.

Explanation of the status codes.

Program-name         Package-ID  Status
UMIBIO               NESC1088/01 Arrived

Machines used:
Package-ID     Orig.Computer                       Test Computer
NESC1088/01    IBM 3081                            

3. DESCRIPTION OF PROGRAM OR FUNCTION - UMIBIO is an internal dosimetry model developed for estimation of the urinary concentration of natural uranium excreted at various times after an inhalation exposure to yellowcake (dried at high and at low temperatures) or ore dust. Calculations are based either on the single exposure intake variable or for continuous exposure on the intake rate variable. The user may change the default intake variables, specify single versus continuous exposure and one or both exponential terms for the systemic calculations.


4. METHOD OF SOLUTION - UMIBIO uses the model developed by the Task Group on Lung Dynamics of the International Commission on Radiological Protection (ICRP) to describe the deposition and retention of inhaled radioactive material in the human respiratory tract and its clearance into the blood. The metabolic model assumes that 11 percent of the uranium reaching the blood is deposited in kidney tissues and is subsequently excreted with a 15-day half-life. It is also assumed that 67 percent of the uranium reaching the blood is excreted within 24 hours without being deposited in any organ. The systemic uptake by all other organs is 22 percent; this uranium is subsequently released back to the blood in accordance with a power function which may be represented by the sum of two exponential functions as recommended in ICRP-30.


5. RESTRICTIONS ON THE COMPLEXITY OF THE PROBLEM - Maxima of - 
   40-day time interval between specimen collections 
Subsequent excretion of the uranium in organs other than the kidney, about 4 percent of that initially reaching the blood, is ignored.


6. TYPICAL RUNNING TIME - Each sample problem required less than 9 CPU seconds on an IBM3033.


7. UNUSUAL FEATURES OF THE PROGRAM - New experimental data that illustrate the dependence of lung solubility in the thermal history of the inhaled yellowcake are incorporated into the model.


8. RELATED AND AUXILIARY PROGRAMS - 


9. STATUS
NESC1088/01: 23-MAY-2001 Masterfiled Arrived


10. REFERENCES  - 
- International Commission on Radiological Protection, Limits for 
  Intakes of Radionuclides by Workers, 
  ICRP Publication 30, Pergamon Press, New York, July 1978. 
- International Commission on Radiological Protection, 
  Recommendations of the International Commission on Radiological 
  Protection, 
  ICRP Publication 26, Pergamon Press, New York, January 1977. 
NESC1088/01:
- R.E. Alexander, R.B. Neel, J.S. Puskin, and A. Brodsky:
  Internal Dosimetry Model for Applications to Bioassay at Uranium
  Mills
  NUREG-0874 (July 1986).
- L. Eyberger:
  UMIBIO Tape Description
  NESC Note 87-98 (September 21, 1987).


11. MACHINE REQUIREMENTS - 1500 Kbytes of memory are required for compilation and execution on an IBM3033.


12. PROGRAMMING LANGUAGE(S) USED -
NESC1088/01: FORTRAN-77 


13. OPERATING SYSTEM UNDER WHICH PROGRAM IS EXECUTED - MVS (IBM3033), VM/CMS (IBM4331).


14. OTHER PROGRAMMING OR OPERATING INFORMATION OR RESTRICTIONS - The proprietary CA-DISSPLA graphics software (see http://www.gaeinc.com), used by UMIBIO, is not included. If CA-DISSPLA is not available or graphical output is not required, the call to subroutine DISPLT should be eliminated from the MAIN routine.


15. NAME AND ESTABLISHMENT OF AUTHORS - 
          R.E. Alexander, R.B. Neel, J.S. Puskin, and A. Brodsky 
          Office of Nuclear Regulator Research 
          U.S. Nuclear Regulatory Commission 


16. MATERIAL AVAILABLE -
NESC1088/01:
UMIBIO Source Program (FTN)                
UMIBIO Sample Problem 1 Input              
UMIBIO Sample Problem 2 Input              
UMIBIO Sample Problem 3 Input              
Control Information                        
UMIBIO Sample Problem 1 Output             
UMIBIO Sample Problem 2 Output             
UMIBIO Sample Problem 3 Output             
report                   NUREG-0874 (July 1986)                     REPPT
prog. note               NESC Note 87-98 (September 21, 1987)       NOTPT


17. CATEGORIES  - 

- G.  Radiological Safety, Hazard and Accident Analysis


Keywords: inhalation, radiation doses, respiratory system, uranium

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